Tuberculosis is a diffcult
disease to treat the reasons are tubercle bacilli grow slowly,dividing
once in 1 to 2 days .it leads to the organisms are tend to develop resistence
to the chemotherapuetic agents and multi drug resistent (MDR) bacilli are will
rise .
generally
tuberculosis disease is treated by using first line drugs and second
line drugs ..both first and second line drugs are devided by 2 types .one is
bactericidal n another one is bacteriostatic.
1.firstline drugs:
bactercidal:
example drugs; isonicotinic acid hydrazide,sreptomycin and
rifampcin
bacteriostatic: etahmbutol
and thiacetazone
2.second line drugs:
bactercidal: fluoroquilones ,capreomycin and kannamycin
bactereocidal: ethionamide,cyclosterine
and clofazimine
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